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RE: WHI :  Hormones and Stroke Risk From: Myer Bornstein (mborn@massmed.org) Wed May 28 17:51:11 2003 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Joe Cutchin: "Re: Hormone-Taking Is Linked to Dementia" Previous message: RModugno@aol.com: "Food for thought" In reply to: Braun, R. Daniel: "RE: WHI :  Homones and Stroke Risk" Next in thread: art fougner, md: "Re: WHI :  Hormones and Stroke Risk" Reply: art fougner, md: "Re: WHI :  Hormones and Stroke Risk" “Estrogen plus progestin therapy increased the risk for probable dementia in postmenopausal women aged 65 years or older. In addition, estrogen plus progestin therapy did not prevent mild cognitive impairment in these women.” Note that the study only showed PROBABLE dementia and did not prevent mild cognitive impairment. Hasn’t been shown there is a slight decrease in cognitive impairment as people age. I also agree with Dan that study has flaws. What happens when a menopausal women starts on HRT in the early fifties? I do not think all the answers are in at present, BUT the media is harping on it aging. . the call are restarting to come in to the office what should I do. As it has been stated by others on the list we will need to CYA. Myer -- Myer S. Bornstein, MD, MMM, FACOG, FACPE, CPE -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Braun, R. Daniel Sent: Wednesday, May 28, 2003 9:32 AM To: Multiple recipients of list OB-GYN-L Subject: Re: WHI : Homones and Stroke Risk Excuse ME!!!!!!!!!!!!!!!! We have to remember that all of this information is coming from a single study that is being reported 15 different ways. How many academic careers is this making?? This may well be a Large randomized, controlled, double blinded study. But it is still just ONE study. We all agreed that it had many flaws in it when it was first reported. It still has all those same flaws. e.g. in the dementia portion, the average length of time in the study was 4 years. Prior studies showed it took either 7 years or a higher dose of estrogen to make any beneficial difference in outcomes. Remember the still unvalidated “Zeta” statistic!!!!!!!!!! Just because the media are hyping the hell out of this ONE study, doesn’t mean that we have to buy into it. WE can ask for more studies with a different population, etc. Remember if you tell a lie often enough, no matter how egregious it is, people will start to believe it. Dan -----Original Message----- From: DoctorJoe@aol.com [mailto:DoctorJoe@aol.com] Sent: Wednesday, May 28, 2003 7:56 AM To: Multiple recipients of list OB-GYN-L Subject: Re: WHI : Homones and Stroke Risk In a message dated 5/28/03 07:06:54, dkrell@msn.com writes: Conclusions Estrogen plus progestin increases the risk of ischemic stroke in generally healthy postmenopausal women. Excess risk for all strokes attributed to estrogen plus progestin appeared to be present in all subgroups of women examined. So I guess God INTENDED women to have menopause - maybe because of the apple and the serpent and all that stuff about leading poor Adam astray - and if we try to AVOID it, something bad might happen. Geeze! Joe P. Next message: Joe Cutchin: "Re: Hormone-Taking Is Linked to Dementia" Previous message: RModugno@aol.com: "Food for thought" In reply to: Braun, R. Daniel: "RE: WHI :  Homones and Stroke Risk" Next in thread: art fougner, md: "Re: WHI :  Hormones and Stroke Risk" Reply: art fougner, md: "Re: WHI :  Hormones and Stroke Risk"

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