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Re: metformin and PCOS From: mperloe@ivf.com ("mperloe@ivf.com") Wed Feb 26 16:28:50 2003 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: mperloe@ivf.com: "Re: Chanced of a Hysterosalpingography effecting ovulation or causing a sudden LH Surge." Previous message: mperloe@ivf.com: "Re: pregnancy question" Maybe in reply to: Dr Ron Jewell: "metformin and PCOS" How does one diagnose insulin resistance? Unless you are doing a insulin glucose clamp study, you are only guessing at resistance. You can measure hyperinsulinemia, but many insulin resistant patient have normal insulin levels. Go back and read the original papers. The findings suggest if the androgens are elevated and cycles irregular, metformin works well. I now utilize metformin in almost all WHO typeII patients as first line therapy and only add in clomiphene or letrozole after a minimum of three months of therapy including a low glycemic diet. Original Message: ----------------- From: rje1@bigpond.net.au (Dr Ron Jewell) ----------------- Date: Tue, 25 Feb 2003 08:10:12 -0600 ----------------- To: ob-gyn-l@mail.medispecialty.com Subject: metformin and PCOS I have used metformin in PCOS patients with documented insulin resistance to induce ovulation with good success. Does anyone have any experience with the obese PCOS patient without insulin resistance? Any role for the drug? Comments invited. -- Ron Jewell Bunbury WA -------------------------------------------------------------------- mail2web - Check your email from the web at -------------------------------------------------------------------- http://mail2web.com/ . -------------------------------------------------------------------- Next message: mperloe@ivf.com: "Re: Chanced of a Hysterosalpingography effecting ovulation or causing a sudden LH Surge." Previous message: mperloe@ivf.com: "Re: pregnancy question" Maybe in reply to: Dr Ron Jewell: "metformin and PCOS"

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