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Re: Atypical complex hyperplasia / endometrial cancerFrom: Joanne Bulley, MD (islesannie@yahoo.com)Fri Feb 21 06:51:45 2003
Case #1 -- first recommendation is hyst by any route - if she refuses a hyst then continuous progesterone (20mg MPA daily) with biopsies every 6 months. The first patient I had like this that did not want a hyst was put on this regimen by the gyn-onc I sent her to for a second opinion. As long as she was on the MPA she was ok - but when she went off of it the biopsy in 6 or 12 months was right back there. She finally had the hyst rather than taking a daily medicine and getting biopsied. #2 -- I'd probably opt for TAH BSO with path evaluation for depth and grade to determine whether or not to do nodes. I suppose you could do a TVH BSO and then go abdominally for nodes if the path eval justified it (grade 2-3 or invasion >50%)
-- Joanne Bulley, MD Keene, NH, USA
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