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Antiphospholipid Syndrome QuestionsFrom: Cyndi Rains (cyndirains@attbi.com)Thu Feb 13 17:41:28 2003
Hello- I am not a physician, I am a pediatric nurse, but please please answer my questions!! I am 30 years old, I have had a total of 4 miscarriages. Two early m/c at 6 weeks in 2000 (blighted ovum), Then in 2001 was dx/d with APS and put on baby aspirin. Delivered a healthy baby boy in Oct 2001. :) In September 2002, m/c at 5 weeks on baby aspirin, and recently in Jan 2003 had another m/c at 6 weeks, also on baby aspirin. My ANA was previously +, but now -. My anticardiolipin was + in Sept. The rheum told me to take baby aspirin every day. So after seeing a RE in Dallas I was told that I would need heparin in addition to baby aspirin with next pregnancy. Questions: 1) What is the difference in outcomes with heparin vs LMWH? (I have heard less SE with LMWH although it is more expensive) 2) Should I ask for further testing to r/o low blocking antibodies, leukocyte antigens, or NK cells? When is predisone or IVIG indicated? 3) I was also told that I have fibromyalgia- (muscle tenderness, poor sleep patterns)-Should I be treated for this- is this somehow related to the APS/miscarriages? 4) What are the pregnancy outcomes or congential anomalies r/t baby aspirin and heparin? (my husband thinks it is too risky) Thank you in advance for your response. I am a pediatric nurse in Dallas, Texas and would like to fill our house with little ones. Look forward to your response.
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