Re: ERT/HRT- personal prescribing trend

From: Efrain Ramirez (eramirezt@coqui.net)
Fri Oct 25 22:09:33 2002


Each case must be individualized - takes a lot more time but it'd worth it --

At Wed, 16 Oct 2002, Zach Newton wrote: >
>The noise level in the role of use of ERT/HRT exceeds the specs on
>commercial grade ear protectors.
>The signal level has become garbage on the screen.
>
>Take any EBM you like, then place your bet.
>
>One thing rings true: it makes sense to assess and recommend on basis of
>individual risk/benefit
>analysis. Actually, that truism is meaningless, as there is no standard for
>such assessment.
>
>I digress to common sense and some science.
>
>Bad things happen to those who hold bad cards more often then to those who
>hold good cards.
>The baggage carried by bad card holders should not burden potential benefit
>to the good
>card holders. Life is not fair.
>
>The patient population in the pre,peri,post menopausal age group that I see
>are on average
>in generally good health. Heavy duty morbidity is certainly represented, but
>lightly on a numbers
>basis.
>
>Big morbidity translates into premature death risk. Other than vasomoter
>instability, where is
>there indication for long term ERT/HRT here?
>
>For the vigorously healthy, I passionately recommend ERT/HRT, absent a
>medical reason or patient objection.
>
>Trend mentioned in subject line is toward increased use of transdermal
>delivery in the belief that
>avoidance of first hepatic passage could reduce multiple risk concerns
>fostered by induction of hepatic enzyme
>systems with oral route.
>
>--
>Zach Newton
>Z. B. Newton, III, M.D.
>Atlanta/Gyn
>

--
"Life is neither the notes nor the silence between the notes, but the music that
 arises out of sound and silence felt as a living whole. Stop choosing...between
 chaos and order, and live at the boundary between them, where rest and action
  move together..." David Whyte




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