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Re: ERT/HRT- personal prescribing trend From: Joanne Bulley, MD (islesannie@yahoo.com) Sun Oct 20 11:14:21 2002 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Mark Perloe: "Re: Gyn: PCO" Previous message: Dr. Abdelhamid Attia: "Re: ERT/HRT- personal prescribing trend" I agree - I have been convinced it wasn't the estrogen - but MANY medical people - providers of care, cancer surgeons, etc have been very vocal on the estrogen = breast cancer commentaries. And that is a hard line to counter - even when there is good data. Thanks for the article refernce. Joanne At Sun, 20 Oct 2002, Dr. Abdelhamid Attia wrote: > >No! It is not the estrogen. > >A study done by Shairer et al., 2000 analyzing the follow-up data of 46,355 postmenopausal women found a 1% (0.01) yearly increase in the RR of developing a breast cancer in estrogen only users versus an 8% (0.08) yearly increase in RR in estrogen+progetin users. This means that after 5 years of use there would be a 5% and 40% increase in the RR of breast cancer in ERT versus HRT users (RR 1.05 & 1.4 respectively). > >So, it may be the progestin added or a combined effect that leads to the increased incidence of breast cancer. > >Shairer et al. Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer Risk. JAMA 2000; 283:485-491 > >-- >Abdelhamid Attia > -- Joanne Bulley, MD Keene, NH, USA Next message: Mark Perloe: "Re: Gyn: PCO" Previous message: Dr. Abdelhamid Attia: "Re: ERT/HRT- personal prescribing trend"

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