Re: Gyn: PCO

From: Charlie Chambers (cchamber@gorge.net)
Sat Oct 19 16:28:08 2002


Mark,

Please clarify. How do you select patients for treatment, i.e. diagnose anovulatory hyperandrogenism?

On Friday, October 18, 2002, at 05:05 PM, Mark Perloe wrote:

> At 09:39 PM 10/15/2002 -0500, you wrote:
>
> Me Three - Agree!
>
> I was about to post why would you use an insulin sensitizing drug when
> there isn't insulin resistence? But Jay & Betsy beat me to it.
>
> Cause you don't diagnose insulin resistance with these tests. If it
> looks like PCOS, it is PCOS unless you have another explanation.
>
> Metformin numerous benefits that will for many promote long term health
> benefits.
>
> Please read the original metformin papers and you will see that in none
> of those papers was fasting insulin levels an issue. If you insist on
> wanting to see abnormal values, the two hour insulin level above 50 is
> the best indicator. But when correlated with clamp studies, LDL and TG
> elevations were strong predictors.
>
> Mark Perloe, M.D.  
> Georgia Reproductive Specialists
> 5445 Meridian Mark Rd, Suite 270, Atlanta, GA 30342
> 404-843-2229
>
> Live Chat Monday evenings 8:00-9:00 p.m. ET
>
= ************************************************************************** Charlie Chambers

Hood River, OR USA cchamber@alumni. rice. edu

"I'm a goin fishin. Yeah, I'm goin fishin And my baby's goin fishin too!" Taj Mahal

************************************************************************

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Mark,

Please clarify. How do you select patients for treatment, i.e. diagnose anovulatory hyperandrogenism?

On Friday, October 18, 2002, at 05:05 PM, Mark Perloe wrote:

<excerpt>At 09:39 PM 10/15/2002 -0500, you wrote:

Me Three - Agree!

I was about to post why would you use an insulin sensitizing drug when

there isn't insulin resistence? But Jay & Betsy beat me to it.

Cause you don't diagnose insulin resistance with these tests. If it looks like PCOS, it is PCOS unless you have another explanation.

Metformin numerous benefits that will for many promote long term health benefits.

Please read the original metformin papers and you will see that in none of those papers was fasting insulin levels an issue. If you insist on wanting to see abnormal values, the two hour insulin level above 50 is the best indicator. But when correlated with clamp studies, LDL and TG elevations were strong predictors.

<bold><italic><fontfamily><param>Times New Roman</param><color><param>0000,8080,8080</param><bigger><bigger><bigger>Mark Perloe, = M.D.</bigger></bigger></bigger></color></fontfamily></italic></bold><fontfamily><param>Times New Roman</param><color><param>0000,8080,8080</param> </color></fontfamily> 

<bold><underline><color><param>1999,1999,FFFF</param>Georgia Reproductive Specialists

</color></underline></bold>5445 Meridian Mark Rd, Suite 270, Atlanta, GA 30342

404-843-2229

Live <underline><color><param>1999,1999,FFFF</param>Chat Monday evening</color></underline>s 8:00-9:00 p.m. ET

= </excerpt>**************************************************************************

Charlie Chambers

Hood River, OR USA

cchamber@alumni. rice. edu

"I'm a goin fishin.

Yeah, I'm goin fishin

And my baby's goin fishin too!"

Taj Mahal

************************************************************************ --Apple-Mail-2-921085102--





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