Re: Puzzling case

From: Braun, R. Daniel (rbraun@iupui.edu)
Thu Oct 10 11:56:04 2002


Right meaning she doesn't withdraw from ESTROGEN and progestin. Meaning something is wrong with her endometrium and she needs a hysteroscopy.

-----Original Message----- From: Richard Chudacoff, MD [mailto:rchudacoff@mylinuxisp.com] Sent: Thursday, October 10, 2002 9:59 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Puzzling case

While she was on OCPs

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Richard Chudacoff, MD

-----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net]On Behalf Of Braun, R. Daniel Sent: Wednesday, October 09, 2002 10:46 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Puzzling case

The original post said that one year ago withdrawal bleeding ceased.

-----Original Message----- From: Richard Chudacoff, MD [mailto:rchudacoff@mylinuxisp.com] Sent: Wednesday, October 09, 2002 9:56 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Puzzling case

She stopped about 4 months ago

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Richard Chudacoff, MD

-----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net]On Behalf Of Dr. John Provatopoulos B.Sc. M.D.C.M. F.R.S.C. Sent: Wednesday, October 09, 2002 9:11 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Puzzling case

At Wed, 9 Oct 2002, Braun, R. Daniel wrote: > >NOTE: One year ago, her withdrawal bleeding to Oral Contraceptive Pills >(ESTROGEN and Progestin) ceased. She not only doesn't withdraw from >estrogen, she also does not withdraw from estrogen and progestin. >HYSTEROSCOPY HYSTEROSCOPY > >Dan > >-----Original Message----- >From: Tony Blair [mailto:antoineb@cgocable.ca] >Sent: Wednesday, October 09, 2002 12:47 AM >To: Multiple recipients of list OB-GYN-L >Subject: Re: Puzzling case > >If the pelvic US is normal, the diagnosis would be "hypogonadotrophic >hypogonadic amenorrhea" ( low GnRH and low E3 : no bleeding with Provera >). Sheehan, Asherman, hysteroscopy ????? >Remember : common things are common... > >The treatment should be HRT (cyclic) or OC depending on the need for >family planning or not, because this women is at risk for osteoporosis >(low E3) > >Just my opinion. > >Tony Blair Ob/Gyn >Canada >

>>>----- Original Message ----- >From: Richard <mailto:rchudacoff@mylinuxisp.com> Chudacoff, MD >To: Multiple recipients of list OB-GYN-L ><mailto:ob-gyn-l@mail.medispecialty.com> >Sent: Monday, October 07, 2002 7:37 PM >Subject: Puzzling case > >I have a patient who came to see me today, for a second opinion, because >of amenorrhea and headaches. She was noted to have irregular cycles, and >therefore FSH and LH were performed. Both FSH and LH were < 0.7 mIU/ML. >Quantitative beta HCG was negative. Provera challenge times 3 noted no >withdrawal bleeding. Prior to one year ago, she had regular withdrawal >bleeding on oral contraceptive pills. Approximately one year ago >withdrawal bleeding ceased. Comprehensive metabolic panel was normal, >with a fasting glucose of 97 mg per deciliter, and a normal prolactin. >I had seen patient previously, a considered a diagnosis of polycystic >ovarian syndrome, and she was started on Glucophage. An

endocrinologist >and Dallas ordered a 3-hour glucose tolerance test, which had an >elevated two-hour specimen of 162 mg per dl. MRI of the brain noted no >evidence of pituitary mass, nor absence of the pituitary gland. > >Physical exam notes in obese 31-year-old female, 239 pounds, 5 ft. 6 >in.. She is mild right lower quadrant pain, and although difficult to >evaluate, there is an impression of a mass. She is scheduled for a >pelvic ultrasound in two days. > >By question is this, other than in estradiol level, and an Inhibin >level, which other studies should be drawn? Can one draw a GnRH level? > >Richard Chudacoff, MD, FACOG

Richard its not clear if she has been on the pill since one year ago .

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                                 Take care, John




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