Re: WHI & HRT

From: WHRA (whra@mindspring.com)
Tue Jul 9 18:06:03 2002


Actually no, there has been a lot of data regarding fractures as the end point and not necessarily BMD. you are so right....SERMS and Bisphosphonates are looking better. Now all we have to do is get those that were "raised on estrogen" to change a little

JK

Jay M. Kulkin, MD MBA FACOG Women's Health Resource Associates 3475 Oak Valley Road Suite 2640 Atlanta, Georgia 30326 404-841-0034 Fax: 404-841-0054

>----- Original Message -----
From: "Betsy Hyde" <elishyde@mindspring.com> To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@mail.medispecialty.com> Sent: Tuesday, July 09, 2002 6:47 PM Subject: Re: WHI & HRT

> At 2:55 PM 7/9/02, Douglas Krell wrote:
> >Patients will still have concerns about vasomotor symptoms and the
> >prevention of osteoporosis. So as long as vasomotor sympotms persist,
the > >products can be used then abandoned as soon as possible. I have many of
my > >HRT patients on low dose Aspirin and or a statin drug. Pravachol ois the
> >only one that does not require LFT monitoring. As for osteoporosis
> >prevention and treatment, there are great drugs for that. Evista, early
on, > >then later bisphosphonates
>
> I think that is the take home message that is coming out these days...use
> short-term estrogen for symptom relief, and treat the other stuff (BMD,
> cardiac disease) with something which is more specific, more effective.
>
> Isn't the WHI data the first to suggest reduction of fractures vs increase
> in BMD which most of the other studies have used as an endpoint?
>
> I think the SERMs are looking a lot better....
>
> Betsy Hyde CNM
>





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