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Re: Protein creatinine ratio From: Braun, R. Daniel (rbraun@iupui.edu) Fri Mar 15 22:18:41 2002 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Braun, R. Daniel: "Re: cystoscopy after hyst" Previous message: jkulkin-whra: "Re: Blues paying 'second procedure' for Postpartum t/l" Maybe in reply to: Montgomery, Lynn MD: "Protein creatinine ratio" Next in thread: Joanne Bulley, MD: "Re: Protein creatinine ratio" Reply: Joanne Bulley, MD: "Re: Protein creatinine ratio" Actually according to a very well done study about 10 years ago, the dip does not correlate at all with the 24 hour total. In the study they had idps that were negatiove in women who had over 4 grams in their 24 hour sample and 4+ on dips in women who had 200 mg in the 24 hour sample. The protein is not excreted in a steady manner but in peaks and valleys. Dan -----Original Message----- From: Steve & Eryl RaymondTo: Multiple recipients of list OB-GYN-L Sent: 3/15/2002 4:57 PM Subject: Re: Protein creatinine ratio You're quite right, there is a correlation, and it probably is close enough for clinical use, but I was thinking you were asking if it could be possible to predict exactly - see your question at the bottom. On the other hand what does it tell you in an obstetric population that you can't tell from a simple dipstick? stray "Montgomery, Lynn MD" wrote: > This is why I ask. Abstract from this years SMFM meeting: > > "Prospective prediction of 24 hour proteinuria by spot protein > creatinine ratio. Binno, et.al. > > Results: Ninety five patients completed the urine collections > for data analysis. The Peason coefficient for the correlation > between the measured and the predicted 24 hour urine protein > was 0.903, with R-squared value of 0.815 and a P < .001. The > 24 hour proteinuria < 300mg was accurately predicted in 63 out > of 68 patients, proteinuria between 300mg and 5 grams was > accurately predicted in 20 out of 23 patients and proteinuria > > 5 grams was accurately predicted in all remaining cases. > > Conclusion: These results confirm that the spot Protein Creatinine > Ratio is a highly reliable assessment for the degree of proteinuria > in the pregnant population. Using PCR will enhance patient care > and will be cost saving as well." > > So if it can't be done, how did they do it? > Lynn > > > This may be a stupid question, but does anybody know how to convert a spot > > protein creatinine ratio into an equivalent total 24 hour protein amount? > > Lynn > > -- > > Dr.S.H. Raymond > Head of Department of O & G > Empangeni Hospital > South Africa 3880 > Phone: (+27) 35-7721111 > Fax: (+27) 35-7922596 -- Dr.S.H. Raymond Head of Department of O & G Empangeni Hospital South Africa 3880 Phone: (+27) 35-7721111 Fax: (+27) 35-7922596 Next message: Braun, R. Daniel: "Re: cystoscopy after hyst" Previous message: jkulkin-whra: "Re: Blues paying 'second procedure' for Postpartum t/l" Maybe in reply to: Montgomery, Lynn MD: "Protein creatinine ratio" Next in thread: Joanne Bulley, MD: "Re: Protein creatinine ratio" Reply: Joanne Bulley, MD: "Re: Protein creatinine ratio"

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