Re: Protein creatinine ratio

From: Steve & Eryl Raymond (eryl@intekom.co.za)
Fri Mar 15 14:55:08 2002


You're quite right, there is a correlation, and it probably is close enough for clinical use, but I was thinking you were asking if it could be possible to predict exactly - see your question at the bottom. On the other hand what does it tell you in an obstetric population that you can't tell from a simple dipstick? stray

"Montgomery, Lynn MD" wrote:

> This is why I ask. Abstract from this years SMFM meeting:
>
> "Prospective prediction of 24 hour proteinuria by spot protein
> creatinine ratio. Binno, et.al.
>
> Results: Ninety five patients completed the urine collections
> for data analysis. The Peason coefficient for the correlation
> between the measured and the predicted 24 hour urine protein
> was 0.903, with R-squared value of 0.815 and a P < .001. The
> 24 hour proteinuria < 300mg was accurately predicted in 63 out
> of 68 patients, proteinuria between 300mg and 5 grams was
> accurately predicted in 20 out of 23 patients and proteinuria
> > 5 grams was accurately predicted in all remaining cases.
>
> Conclusion: These results confirm that the spot Protein Creatinine
> Ratio is a highly reliable assessment for the degree of proteinuria
> in the pregnant population. Using PCR will enhance patient care
> and will be cost saving as well."
>
> So if it can't be done, how did they do it?
> Lynn
>
> > This may be a stupid question, but does anybody know how to convert a spot
> > protein creatinine ratio into an equivalent total 24 hour protein amount?
> > Lynn
>
> --
>
> Dr.S.H. Raymond
> Head of Department of O & G
> Empangeni Hospital
> South Africa 3880
> Phone: (+27) 35-7721111
> Fax: (+27) 35-7922596

--

Dr.S.H. Raymond Head of Department of O & G Empangeni Hospital South Africa 3880 Phone: (+27) 35-7721111 Fax: (+27) 35-7922596





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