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Re: Protein creatinine ratioFrom: Montgomery, Lynn MD (LMontgomery@COMMUNITYMED.ORG)Thu Mar 14 12:23:27 2002
This is why I ask. Abstract from this years SMFM meeting: "Prospective prediction of 24 hour proteinuria by spot protein creatinine ratio. Binno, et.al. Objective: The degree of proteinuria is frequently assessed in obstetric patients with preeclampsia, diabetes and other medical complications. The gold standard has been a 24 hour collection of urine. Obviously collecting urine for 24 hours is cumbersome and may frequently result in erroneous results secondary to incomplete collections. In the non-obstetric population, the spot Protein Creatinine Ratio (PCR) is used to assess the degree of proteinuria. This study examined the prospective prediction of the 24 hour proteinuria using the spot PCR in obstetric patients. Study Design: One hundred-twenty antepartum patients with a variety of medical indications, were asked to obtain a 24 hour urine specimen at home, on the day prior to their clinic visit. At their clinic visit they were asked to obtain a single urine sample for the spot PCR. The 24 hour urine protein content was measured in the laboratory. The spot PCR was used to predict the 24 hour urine protein content and the correlation between the measured 24 hour urine protein and the predicted 24 hour urine protein is presented.
Results: Ninety five patients completed the urine collections
for data analysis. The Peason coefficient for the correlation
between the measured and the predicted 24 hour urine protein
was 0.903, with R-squared value of 0.815 and a P < .001. The
24 hour proteinuria < 300mg was accurately predicted in 63 out
of 68 patients, proteinuria between 300mg and 5 grams was
accurately predicted in 20 out of 23 patients and proteinuria
> 5 grams was accurately predicted in all remaining cases. Conclusion: These results confirm that the spot Protein Creatinine Ratio is a highly reliable assessment for the degree of proteinuria in the pregnant population. Using PCR will enhance patient care and will be cost saving as well." So if it can't be done, how did they do it? Lynn -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net]On Behalf Of Steve & Eryl Raymond Sent: Thursday, March 14, 2002 10:31 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Protein creatinine ratio Can't be done. Total urinary excretion varies diurnally. stray "Montgomery, Lynn MD" wrote:
> Hey y'all,
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