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Re: Cigdem Arkuran's ReferenceFrom: Robert J Woolley (wooll005@tc.umn.edu)Tue Jul 31 11:48:00 2001
> With regard to the absence of proteinuria, I have no argument. As I > stated previously, even in eclampsia 7-10% have no proteinuria. However, > we must remember that the great majority of these patients had > proteinuria assessed by simple dipstick methods. 24-hour urine > collections were not performed. There are a couple of publications > which indicate that when compared to a 24-hour urine collection, the > assessment of proteinuria by disptick is far less reliable. Thanks for the comments. When one can't reasonably get a 24-hr urine because of time constraints or whatever, a better substitute than just a dipstick would be the ratio of urine protein (quantitative) to urine creatinine in a single specimen. This ratio has a high correlation with 24-hr urine protein. In fact, by happy coincidence, one doesn't even have to do any math; the conversion is 1:1. That is, if the spot protein/creat ratio is 3, the 24-hr protein can be estimated at 3g. Caveat: although this is true in general internal medicine patients, I do not know that a similar correspondence has been established for women in late pregnancy. However, I still think it will give a better assessment that a dipstick.
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