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Re: ovarian cancer From: art fougner, md (evsono@pipeline.com) Fri May 18 08:07:33 2001 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Douglas Krell: "Re: comments?" Previous message: art fougner, md: "GEN: FDA's Integrity?" In reply to: Jeffrey W. Clemens: "Re: ovarian cancer" Next in thread: Efrain Ramirez: "Re: ovarian cancer" Reply: Efrain Ramirez: "Re: ovarian cancer" folks - the problem with population studies concerning the influence of hormones and cancer is that there is no way to ascertain whether or not selection bias is operative. only with the rapid development in the field of genetics will this issue be addressed. until such time, we are groping in the dark and all poplulation studies should be regarded as suspect. art At Fri, 18 May 2001, Jeffrey W. Clemens wrote: > >Listers, > > If I might elaborate- the model is that the importance of the decrease >in gonadotropins was the prevention of the LH surge and therefore decreased >numbers of ovulatory events, less repair of the ovarian surface epithelium, >less chances for mitosis to go astray, etc.. > >> My impression was that hormones, either pregnancy or replacement, decreased >> the risk of ovarian cancer, probably because it decreased the stimulation of >> the ovarian tissue by gonadotropins (due to negative feedback)... Anyone else >> know anything different? >> >> Joe P. >> >-- >Jeffrey W. Clemens, Ph.D. >Assistant Professor, Biological Sciences >Duquesne University >Pittsburgh, PA 15282 >412-396-4597 >fax-5907 >http://www.home.cc.duq.edu/~clemens/ > -- art fougner, md A series of 1000 cases begins with but a single anecdote. Next message: Douglas Krell: "Re: comments?" Previous message: art fougner, md: "GEN: FDA's Integrity?" In reply to: Jeffrey W. Clemens: "Re: ovarian cancer" Next in thread: Efrain Ramirez: "Re: ovarian cancer" Reply: Efrain Ramirez: "Re: ovarian cancer"

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