Re: ACOG Chicago..a sad story-Heart disease in women

From: jkulkin (jkulkin@mindspring.com)
Thu May 3 05:57:24 2001


Can't extrapolate the PEPI Trial data on micronized progesterone as MI was not a measureable endpoint, only lipid changes. The WHI study wil help us with that when the data is avaialable in 3-4 years. In the interim, I thnk using HRT in these people is as exposes the doc should these people have a repeat MI in year one of HRT. Possibly informed consent is a good idea?

Jay

Larry Glazerman wrote:

> Yeah, but first of all, there was no data in HERS about progestins other
> than MPA, in addition, over the 4 years of the study, the incidence of
> repeat MI was unchanged.
>
> At 05:33 PM 5/2/01 -0500, you wrote:
> >Went to an interactive session. You know, where you use the "audeince
> >participation" device like they do on "who wants to be a
> >millionaire". The topic was HRT. The case posed was, "A 54 yo lady s/p MI now
> >presents with menopausal symptoms i.e., amenorrhea, hot flashes, trouble
> >sleeping etc. They then listed the options for treatment . As I recall
> >they were:
> >
> >HRT
> >SERM
> >Bisphosphonates
> >Belergal
> >There was one more but I forget what it was though it was irrelevant.
> >
> >An incredible 71% responded they would give the patient HRT. Clearly they
> >were unaware of the HERS data indicating an increased risk of repeat MI in
> >the first year in this group of women with known heart
> >disease. . Pretty troubling to think this is happening.
> >
> >Jay
> >
> >"art fougner, md" wrote:
> >
> > > and that should read "courts, not course." of course ;)
> > >
> > > art
> > >
> > > At Fri, 27 Apr 2001, RModugno@aol.com wrote:
> > > >
> > > > <A
> > HREF="http://www.ctnow.com/scripts/editorial.dll?fromspage=CG/articles/business.htm&categoryid=&bfromind=377&eeid=4458465&eetype=article&render=y&ck=&ver=2.8&377&eeid=4458465&eetype=article&render=y&ck=&ver=2.8&icle&render=y&ck=&ver=2.8>>
> > >Robert Modugno MD MBA FACOG
> > > >Marietta, GA
> > >
> > > --
> > > art fougner, md
> > >
> > > A series of 1000 cases begins with but a single anecdote.
>
> Larry R. Glazerman, MD
> Ob-Gyn at Trexlertown
> 610-402-0161
> l.glazerman@rcn.com





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