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Re: Profilactic HisterectomyFrom: Mehmet H. Ergeneli (ergeneli@hotmail.com)Thu Apr 26 09:50:35 2001
The rate of endometrial cancer occurance among tamoxifen users who were administered 20 mg/day in the U.S. National Surgical Adjuvant Breast and Bowel Project was 1.6 per 1000 patient years, compared with 0.2 per 1000 patient years among control patients taking placebo. The stage, grade, histology, or biology of tumors that develop in tamoxifen users was no different from those that arise in the control population. On the basis of these data, monitoring patients regularly would be more appropriate than performing prophylactic hysterectomy. Mehmet H. Ergeneli, M.D. Private practice
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