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Re: breastfeeding on MgSO4From: ainsron@msn.comFri Mar 23 14:05:31 2001
Your pediatricians need to review the literature, it is not contraindicated. This is a summary from Briggs, Drugs in Pregnancy and Lactation: Breast Feeding Summary Magnesium salts may be encountered by nursing mothers using over-the-counter laxatives. A study in which 50 mothers received an emulsion of magnesium and liquid petrolatum or mineral oil found no evidence of changes or frequency of stools in nursing infants (33). In 10 preeclamptic patients receiving magnesium sulfate, 1 g/hour IV during the first 24 hours after delivery, magnesium levels in breast milk were 64 µg/mL as compared with 48 µg/mL in nontreated controls (34). Twenty-four hours after stopping the drug, milk levels in treated and nontreated patients were 38 and 32 µg/mL, respectively. By 48 hours, the levels were identical in the two groups. Milk:plasma ratios were 1.9 and 2.1 in treated and nontreated patients, respectively. The American Academy of Pediatrics considers magnesium sulfate to be compatible with breast feeding (35).
At Thu, 22 Mar 2001, elizabeth bary wrote:
>
-- Ronald E. Ainsworth, MD
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