Re: Aredia

From: RModugno@aol.com
Thu Mar 22 21:33:08 2001


In a message dated 3/21/01 11:42:52 PM Eastern Standard Time, DoctorJoe@aol.com writes:

> The osteoblast inhibitor drugs are used for a variety of reasons, including
> osteoporosis from menopause, bone destruction by cancers of various kinds
> (my
> father was on one of the IV forms for multiple myeloma), etc, etc. They
> inhibit osteoclastic activity, allowing osteoblast "overwork", leading to
> increased bone mass. I think one theory is that they HELP damaged areas,
> besides just retarding generalized osteoporosis. Probably the doctor who
> prescribed this was thinking of both at the same time.
>
> Joe P.
>

Isn't Aredia also used to treat hypercalcemia associated with metastatic breast cancer? I believe it was used in a patient of mine who was pregnant, had hepatic metastases from breast cancer and then developed pancreatitis secondary to hypercalcemia - she was one sick lady!

Robert Modugno MD MBA FACOG Marietta, Ga





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