Re: Labor-Inducing Drug Associated With 8 Deaths
From: art fougner, md (evsono@pipeline.com)
Fri Dec 22 14:02:52 2000
fact remains that despite all the deaths secondary to motor vehicle
accidents, i don't see the demand to cease and desist the sale of
automobiles. it's usually not the drug, folks, just the way the drug is
being used.
art
At Fri, 22 Dec 2000, Braun, R. Daniel wrote:
>
>I don't know how many there were. It is my speculation that there were a lot
>more, but I DON'T know.
>Dan
>
>R. Daniel Braun, MD FACOG
>Clinical Professor
>Department of Obstetrics and Gynecology
>Indiana U. School of Medicine
>Indianapolis, IN 46202
>
>OBGYN.net
>International Representative for United States
>
>Certified AllExperts Expert
>Check out my bio/ratings page!
>http://www.allexperts.com/displayExpert.asp?Expert=1236
>
>-----Original Message-----
>From: Griffiths Malcolm (RC9) Luton & Dunstable Hospital TR[mailto:Malcolm.Griffiths@ldh-tr.anglox.nhs.uk]
>Sent: Friday, December 22, 2000 9:02 AM
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: Labor-Inducing Drug Associated With 8 Deaths
>
>If you tell me that there were many more than eight deaths a year in the USA
>associated with Pitocinon then I'd feel better about the Misoprostol deaths.
>In the UK I don't think we'd come close.
>
>-----Original Message-----
>From: Braun, R. Daniel [mailto:rbraun@iupui.edu]
>Sent: 22 December 2000 13:08
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: Labor-Inducing Drug Associated With 8 Deaths
>
>And how many do you think there were where Pitocin was used?
>
>Dan
>
>R. Daniel Braun, MD FACOG
>Clinical Professor
>Department of Obstetrics and Gynecology
>Indiana U. School of Medicine
>Indianapolis, IN 46202
>
>OBGYN.net
>International Representative for United States
>
>Certified AllExperts Expert
>Check out my bio/ratings page!
>http://www.allexperts.com/displayExpert.asp?Expert=1236
>
>-----Original Message-----
>From: Griffiths Malcolm (RC9) Luton & Dunstable Hospital
>TR[mailto:Malcolm.Griffiths@ldh-tr.anglox.nhs.uk]
>Sent: Friday, December 22, 2000 4:00 AM
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: Labor-Inducing Drug Associated With 8 Deaths
>
>Agreed but eight deaths is still hell of a lot and not something to be
>dismissed.
>
>-----Original Message-----
>From: Steve & Eryl Raymond [mailto:eryl@intekom.co.za]
>Sent: 22 December 2000 08:49
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: Labor-Inducing Drug Associated With 8 Deaths
>
>Malcolm, it's not the drug, but how it has been used that is the likely
>cause of
>the trouble. If you were to use Prostaglandin E2 without due care and
>attention
>to the potential complications and to the dose you could have the same
>scenario.
>
>"Griffiths Malcolm (RC9) Luton & Dunstable Hospital TR" wrote:
>
>> I would be very concerned if even in a large population such as the USA
>that
>> there had been eight deaths associated with induction of labour let alone
>> form induction of labour by an off-label product only being used by a
>> minority of ob/gyns. Death seems to me to e a definite end-point and one
>> that one can't argue with.
>>
>> This information would cause me concerns and I would not be so dismissive.
>>
>> Subject: Re: Labor-Inducing Drug Associated With 8 Deaths
>>
>> >... the drug's
>> >manufacturer, G.D. Searle Corporation, sent a letter to 200,000 health
>care
>> >providers warning them that "Cytotec administration by any route is
>> >contraindicated in women who are pregnant because it can cause abortion."
>> >(The drug is, in fact, used in combination with RU-486, for this specific
>> >purpose.) The company also noted that off-label use of the drug has
>resulted
>> >in reports of uterine rupture, hysterectomy, and the death of mothers and
>> >infants....
>>
>--
>Dr. S.H. Raymond
>Department of Obstetrics & Gynaecology
>Empangeni Hospital
>Private Bag X20005
>Empangeni
>South Africa 3880
>Ph. (+27) (035) 7721111
>Fax (+27) (035) 7922596
>
--
art fougner, md
A series of 1000 cases begins with but a single anecdote.
|
|
