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Re: current CIN 3 in an immunosuppressed patient From: Joanne Bulley (islesannie@yahoo.com) Thu Nov 23 14:10:35 2000 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Joanne Bulley: "Re: Family" Previous message: Garry Siegel: "Re: Family" In reply to: Ron Jewell: "Recurrent CIN 3 in an immunosuppressed patient" I have had patients with HPV based CIN, VaIN and VIN when immunocompromised. It seems like your patient would be an ideal one to use an anti-viral therapy. In the 'olden' days (1980's) one thing we did was use intravaginal 5-FU. We'd do 1 dose weekly for 10 weeks and repeat the pap 4-8 weeks after that. (I'll have to look up what that dose was when I get back home - I'm at my folks in OHIO now) Nowadays you have interferon and other such options. I would probably HPV-type this woman's cervix and then treat woth some anti-viral therapy rather than whittle away at the cervix. Joanne At Wed, 22 Nov 2000, Ron Jewell wrote: > >I have a renal transplant patient, nulliparous age 28 who has now had 3 >LLETZ(LEEP) procedures performed for CIN 3 over a 3 year period. > >Do I keep nibbling away at her cervix? Would HPV typing give any >guidance? She wants to get pregnant in about 2 years time. > >All opinions are welcome. This girl intends to travel to the UK and >Holland next year. Would anyone in the UK or in Holland like to see her >as a patient? > >Regards >Ron Jewell Bunbury Western Australia -- Joanne Bulley, MD, FACOG Keene, NH, USA Take time to smell the roses. Next message: Joanne Bulley: "Re: Family" Previous message: Garry Siegel: "Re: Family" In reply to: Ron Jewell: "Recurrent CIN 3 in an immunosuppressed patient"

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