Re: current CIN 3 in an immunosuppressed patient

From: Efrain Ramirez (eramirez@icepr.com)
Wed Nov 22 20:42:39 2000


I would urge her to get pregnant sooner - HPV typing might help her in her decision making process.

At Wed, 22 Nov 2000, Richard Chudacoff, MD wrote: >
>What about interferon treatment? 5FU?
>
>--
>Richard Chudacoff, MD
>
>-----Original Message-----
>From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net]On Behalf Of Ron Jewell
>Sent: Wednesday, November 22, 2000 8:33 AM
>To: Multiple recipients of list OB-GYN-L
>Subject: Recurrent CIN 3 in an immunosuppressed patient
>
>I have a renal transplant patient, nulliparous age 28 who has now had 3
>LLETZ(LEEP) procedures performed for CIN 3 over a 3 year period. Each
>specimen shows complete excision of the lesion. The last procedure was
>6 months ago.
>
>Unfortunately her last smear shows CIN 1 and on colposcopy there is a
>tiny area of CIN 3, confirmed by biopsy on the new transformation zone.
>Amazingly there is still a reasonable amount of cervix present.
>Presumably she has a high risk HPV type present in association with the
>immunosuppression needed to maintain her transplant. There is no
>obvious disease in the vagina or on the vulva.
>
>Do I keep nibbling away at her cervix? Would HPV typing give any
>guidance? She wants to get pregnant in about 2 years time.
>
>All opinions are welcome. This girl intends to travel to the UK and
>Holland next year. Would anyone in the UK or in Holland like to see her
>as a patient?
>
>Regards
>Ron Jewell Bunbury Western Australia
>

--
"Do not take life too seriously. You will never get out of it alive."

Marianne Williamson





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