Re: ondansetron

From: John Robertson MD (john.robertson@medispecialty.com)
Sun Nov 12 10:36:39 2000


The story takes an interesting twist as the nurse tells me last night she was caught with her fingers down her throat. She says she was already vomiting and she was trying to get out something that was stuck. OTOH she seems better today on the ondansetron. John

PS how do you get "fuf" from Gary Kleinman (in the e-mail address)? John

At Sun, 12 Nov 2000, fuf wrote: >
>> From: john.robertson@medispecialty.com (John Robertson MD)
>> Reply-To: ob-gyn-l@obgyn.net
>> Date: Sat, 11 Nov 2000 11:57:54 -0600
> Anaesthetist suggested Ondansetron, says it doesn't
>> cause those side effects. Briggs says category B. Any experience with
>> this drug? John
>>
>> --
>> J.G.M.Robertson MD, 109-9181 Main St. Chilliwack, B.C. V2P 4M9
>
>J.G.M.,
>
>Yes, I have used ondansetron (Zofran) in many pregnancies and believe it is
>more effective than other antiemetics (in other words, swear by it),
>although some studies seem to say it is no better than others. 4mg IV or PO
>q6h to start. Can double dose if not sufficient.
>
>It is very expensive. Epocrates (very good free app for handhelds) says it
>goes for $147.28 for ten 4mg tabs on online pharmacies. Whereas phenergan
>supps go for $48 for 12 suppositories. Phenergan, compazine, tigan and most
>other antiemetics are category C. I have not seen extrapyramidal effects
>with it. Maybe that might help with approval for insurance plans.
>
>If you have a patient who won't respond to ondansetron, try granisetron
>(Kytril) 1mg IV q 12 h. I have yet to see nausea that does not respond to
>that. I can't believe the price listed for the PO form - two 1mg tabs for
>$94.84! I have only used Kytril when Zofan didn't work.
>
>Gary Kleinman
>MFM/Genetics
>Brigeport Hospital
>Bridgeport CT

--
J.G.M.Robertson MD, 109-9181 Main St. Chilliwack, B.C. V2P 4M9
(604) 793-9988 e-mail john.robertson@obgyn.net
Who is wise and understanding among you?  Let him show it by his good life,
by deeds done in the humility that comes from wisdom.  James 3 vs 13, NIV




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