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Re: Oral Cytotec From: Luis Sanchez-Ramos, MD (sanchez-ramos@worldnet.att.net) Tue Oct 31 19:34:07 2000 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Sierra and/or Gina: "Formatting Responses" Previous message: Paul Prior MD: "Re: ACOG/Cytotec -good news" In reply to: Efrain Ramirez: "Re: Oral Cytotec" Next in thread: Dr. Lynn Montgomery: "Re: Oral Cytotec" I hate to disagree, but 25-50 mcg of orally administered misoprostol is not an effective method for labor induction (unless your definition of success is different than what is in the literature). In fact, oral doses of 100 mcg have not been very effective and are only so when compared to 25 mcg vaginally. It seems that the proper dose is closer to 200 mcg orally. We see no benefit to using it orally. It is easier to remove from the vagina when given by that route, if need be. I discuss the issue of oral vs vaginal in my systematic review in Clin Obstet Gynecol Sept 2000. My good friend from Spain, Jose Luis Bartha, published a nice paper in the september issue of the green journal and he used a single dose of 200 mcg effectively. For those who feel necessary to use the oral route I would recommend 100 mcg. There may be a patient here and there that could respond to 25 mcg! LSR At Tue, 31 Oct 2000, Dr. Lynn Montgomery wrote: > >Rick, >Have been using in orally for about 4 years. Early in my experience with >it, I used it on a rather obese patient (350+) and she just sat there and >smiled all day long-nothing happened. Because I could not really be sure >about the pharmacokenetics (where the cytotec was hiding), I switched to >oral and have used it ever since. I only use it with inpatients. I use the >same doses (25-50 mcg) and get what seems to be an excellent response and >have never had tachysytole/hyperstim. >Lynn > -----Original Message----- > From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net]On Behalf Of Richard >Chudacoff, MD > Sent: Tuesday, October 31, 2000 3:56 PM > To: Multiple recipients of list OB-GYN-L > Subject: Oral Cytotec > > Anyone using oral Cytotec for induction of labor? In patient or office >with monitoring? I read the article in the Green Journal in June by Debra >Wing, comparing the efficacy of oral v. vaginal, and have just induced my >second patient orally. Zero-to-Q-2 minute contractions in two hours, one a >multip and the other primip. Both delivered within 14 hours by SVD. > > Rick > > Richard Chudacoff, MD > > Chudacoff Obstetrics & Gynecology, PLLC > > 15200 Southwest Freeway, #270 > > Sugar Land, TX 77478 > > Tel: 281-277-3900 > > Fax: 281-277-3901 > > rchudacoff@mylinuxisp.com > > Richard.Chudacoff@obgyn.net > > ********************************************************************** > >-- > ********************************************************************** > Neither the confidentiality nor the integrity of this message > > can be guaranteed following transmission on the Internet. > > ********************************************************************** > > ********************************************************************** > Next message: Sierra and/or Gina: "Formatting Responses" Previous message: Paul Prior MD: "Re: ACOG/Cytotec -good news" In reply to: Efrain Ramirez: "Re: Oral Cytotec" Next in thread: Dr. Lynn Montgomery: "Re: Oral Cytotec"

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