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Re: bendectin From: Anna Meenan, MD (annam@uic.edu) Thu Oct 12 16:17:16 2000 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Kathi Wilson: "Re: abortion/placenta previa" Previous message: ainsron@msn.com: "Fri: humor" In reply to: art fougner, md: "Re: bendectin" Next in thread: Braun, R. Daniel: "Re: bendectin" The ORIGINAL formula for Bendectin was apparently 10 mg. dicyclomine, 10 mg. doxylamine, and 10 mg. pyridoxine, but the dicyclomine was dropped in 1976. Unisom contains 25 mg. of doxylamine, so the closest you can come to Bendectin is a half tab of unisom (12.5 mg. doxylamine) with 10 mg of pyridoxine. Bendectin had a coating on it which was supposed to allow it to be absorbed slowly overnight so your tummy would still be happy in the morning (the recommendation was to take it at bedtime) but we used to bite it in half before swallowing when urgent relief was needed during the daytime. Doses as low as 50-100mg. per day of pyridoxine (B6) can cause a peripheral neuropathy, but it usually takes more than that and most people don't have a problem with it. There was a study in Ob-Gyn in 1991 that concluded that pyridoxine alone (25 mg. tid X 3 d.) is effective for nausea and vomiting of pregnancy. Bendectin was removed from the market in 1983. I remember it well, because I was right in the middle of my first pregnancy and I quickly bought up the remaining stock in the hospital pharmacy. -- Anna Meenan, MD, FAAFP At Tue, 10 Oct 2000, art fougner, md wrote: > >is the water muddy enough? this from "the virtual hospital" > >"Bendectin (10 mg of doxylamine succinate and 10 mg of pyridoxine) was >removed from the market, though large studies have not shown evidence of >teratogenicity. " > >anyone with access to an old pdr? > >art > >At Tue, 10 Oct 2000, Len2976@aol.com wrote: >> >>Excuse the typo error--I never claimed to be a secretary! >> >>I believe the correct mix is >> Vit B-6 25 mg + Unisom 10 mg = Bendictin >> >>Lenora McCall, CNM > >-- >art fougner, md > >A series of 1000 cases begins with but a single anecdote. > Next message: Kathi Wilson: "Re: abortion/placenta previa" Previous message: ainsron@msn.com: "Fri: humor" In reply to: art fougner, md: "Re: bendectin" Next in thread: Braun, R. Daniel: "Re: bendectin"

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