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Re: RU486From: Mats O. Bergstrom (mob@mbox301.swipnet.se)Sat Oct 7 15:57:57 2000
>What advantages does the mifepristone (RU486) have >over a methotrexate (MTX)/cytotec termination I just checked Medline and didn't find any study directly comparing mifepristone and methotrexate. There are many single (plus PG) substance studies. MTX is somewhat less effective - authors have found a need for a second dose in quite a few cases. Mifepristone is also probably safer. (Cytotec alone is less but still quite effective.)
>does the prostaglandin (cytotec?) after mifepristone Misoprostol (Cytotec) is the only available PG for oral use. Many studies by now have shown that vaginal administration of Cytotec is significantly more effective than oral, for various indications. Mats Bergstrom, MD Ob Gyn South Hospital Stockholm
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