Re: The death of Cytotec/misoprostol as we know it

From: Paul Prior MD (pprior@clover.net)
Fri Sep 15 18:27:08 2000


On Fri, 15 Sep 2000 17:31:47 -0500, eramirez@icepr.com (Efrain Ramirez) wrote:

>Paul- would you want to see something like this -- hey everyone --this
>is me talking not ACOG Ok?
>
>IMPORTANT DRUG UPDATE CONCERNING THE USE OF INTRAVAGINAL OR ORAL
>MISOPROSTOL IN PREGNANT WOMEN FOR INDUCTION OF LABOR OR ABORTION
>
>Dear Doctor ___________:
>
>The purpose of this letter is to remind you that Cytotec administration
>by any route is not contraindicated in women who are pregnant when use
>in an appropriate fashion. Although Cytotec is not approved by the FDA
>for the induction of labor or abortion . Such "off-label" prescribing
>is legal and is not considered experimental if the use of the medication
>is based on sound, scientific studies.

...deleted...

Such a letter seems based on a reasonable balance between known benefits and the lack of manufacturer submitted FDA data. It would benefit us all for such a letter to be sent out post-haste from ACOG.

--
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