Splenomegaly and pregnancy

From: ainsron@msn.com
Mon Aug 21 11:08:54 2000


I have a 15yo, G1 (who ironically I also delivered) who initially saw a CNM for care and subsequently transferred care to me for high risk pregnancy care because of splenomegaly. She noted a sudden increase in abdominal girth at about 14 weeks and a sonogram showed "massive splenomegaly." F/U ultrasound demostrates the same and on exam her abdomen is asymmetrically enlarged, largest and fullest in LUQ. She has normal hematologic parameters - normal platelets, normal peripheral smear, normal H&H and normal liver function tests. She is quite thin, and I think it would have been noted before if it was present prior to pregnancy. She has had a hematologic consultation with no specific findings or recommendations and I discussed it with a perinatologist who basically said, "Hmm, never seen that before, but I'll look for information." He called me back today after reviewing some information and said it could be a sign of glycogen storage diseases and suggested genetic consultation. Anyone have any other thoughts or suggestions? Thanks

--
Ronald E. Ainsworth, MD




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