Re: Preterm PROM case

From: obgynmd (obgynmd@hotpop.com)
Wed Jul 19 19:11:58 2000


----------------------------------------------- ----- Original Message ----- ----------------------------------------------- From: DoctorJoe@aol.com To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@mail.medispecialty.com> Sent: Wednesday, July 19, 2000 7:31 AM Subject: Re: Preterm PROM case

>
> In a message dated 7/19/00 1:57:38 AM, obgynmd@hotpop.com writes:
>
> << A 26 wk pregnancy, with a h/o prolonged rupture of membranes (for more
than >
> a month), inpatient, received standard doses of steroids.
>
> Phosphatidylglycerol came back positive on a sample of AF. No signs of
>
> infection. No signs of fetal distress. Fetal growth ok on US scans. AFI
>
> shows 'moderate oligo'. >>
>
> How was the AF collected? Did you do an L/S ration or some other
confirmatory > test also? PG can come back falsely positive from bacterial contamination.
I > would be especially suspicious since this baby is so young. (BTW, what IS
the > fetal weight?)
>
> Joe P.
>

According to the notes, AF was collected from a pad. At our facility, the standard test is the PG, which is thought to be more confirmatory than the L/S ratio (?). I believe that the possibility for false positives also depends on the reactive they use at the lab (I'll try to check that out). Although Creasy states (perhaps too categorically), that "Since amniotic fluid obtained from the vagina may be contaminated by substances present there, the PG test theoretically is the only fetal maturity test available that is totally unaffected by contamination". It might only be theoretically.

Last EFW reached 900 g for the 26 wker.

Sing-Hung Chang





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