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Re: Gail Model 1.9From: Joanne Bulley, MD (jbulley@cheshire.net)Thu Apr 27 23:22:51 2000
I find that the women who are totally petrified of Breast Cancer want ANYTHING with any degree of helpfulness to reduce their risk. These will consider taking 5 years of Tamoxifen and perhaps follow through with the 5 year commitment. The women who want to do anything possible to reduce ASCD, stroke, fractures and Alzheimers - take the breast cancer risk of our longevity in stride and want to not take 5 years of Tamoxifen - or if after menopause want to take their HRT. So - there is not ONE answer as we do not have the full EBM - scientific answer. Off on a tangent ... or maybe not ... Prostate Cancer - another hormonally responsive tissue that seems the more years men live the greater the chance of prostate cancer. (similar to breast cancer) Would men consider taking - or will someone consider designing and doing the study - of Serum Testosterone Receptor Modulators and reduction in Prostate Cancer? What side effects, including sexual dysfunction would the men consider acceptable for reducing their cancer risk? What if reducing men's testosterone also reduced ASCD? Being a gynecologist, I have not kept up on whether any of these studies are being done, so Mea Culpa if these are ignorant thoughts / comments. To quote someone else from this list - "It is just my opinion and I could be wrong"
-- Joanne Bulley, MD Keene, NH, USA
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