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Re: Asymptomatic bacteriuriaFrom: Geffrey Klein, MD (gklein@icsi.net)Sun Apr 23 09:41:37 2000
At 9:34 AM -0500 on 4/23/00, DoctorJoe@aol.com wrote:
> In a message dated 4/23/00 3:11:16 AM, rupakray@caltiger.com writes: per the PDR Although it is classified as a pregnancy category B drug for use during pregnancy, nitrofurantoin can induce hemolytic anemia in G6PD-deficient patients and in patients whose RBCs lack sufficient quantities of reduced glutathione. Since neonates exhibit this latter condition, generally it is wise to avoid the use of this drug during late pregnancy; however, hemolytic anemia in the newborn as a result of in utero exposure to nitrofurantoin has not been reported. Nitrofurantion is contraindicated in pregnancy at term (38-42 weeks gestation), during labor or obstetric delivery, or in neonates < 1 month old. Nitrofurantoin is distributed into breast milk and should be used with caution in breast-feeding women, especially in infants with G6PD deficiency. _______________________ Geffrey H. Klein, MD -- _______________________ geffrey.klein@obgyn.net 200 Medical Center Blvd Suite 103 Webster, TX 77598 (281) 332 6723
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