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Re: TamoxifenFrom: art fougner, md (evsono@pipeline.com)Wed Apr 12 15:12:24 2000
Altho tamoxifen has been used for fibroid control, it has been reported to stimulate growth in some cases. some fibroids, i guess, don't read the book. J Reprod Med 1996 Feb;41(2):119-20 Tamoxifen-induced growth of leiomyomas. A case report. Kang J, Baxi L, Heller D Department of Obstetrics and Gynecology, College of Physicians and Surgeons of Columbia University, New York, New York, USA. BACKGROUND: Tamoxifen, a nonsteroidal estrogen agonist-antagonist, is used in the treatment of breast cancer. CASE: A postmenopausal woman, aged 73, while being treated with Tamoxifen, developed continuous growth of her myomatous uterus, became symptomatic and required surgery. CONCLUSION: Tamoxifen at a dose of 40 mg/d has been associated with endometrial carcinoma. The growth of myomas seen with Tamoxifen in this patient seems to be a result of its direct agonist properties. hope this helps. Art
At Wed, 12 Apr 2000, Eileen or Bernie wrote:
>
-- art fougner, md
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