Re: luteal phase defects

From: guy (venezia.gaetano@mhsil.com)
Fri Apr 7 12:11:45 2000


good points. i was also trained to do two, but has become difficult with pt compliance. the point i made on one bx was in reference to the recent acog audio cme in which the panel of gyn docs admited to doing just one emb at mid luteal phase toward the end of the cycle. (secondary to pt prefernce and pain) i still get a wide range of pain responses to my emb's. what do you think of progest levels...it is in the lit but am not sure it is of much clinical value. (wash univ and st louis univ are doing them) thanks guy

>
>The biopsy should be done later in the luteal phase than midcycle (the
>closer to the menses the better).
>
>And a single biopsy is probably worthless (although may appease the
>patient), as they are found to be out of phase in 60% of the cases, gross
>overcall of ILP. Only repeat biopsy following an out-of-phase bx confirms
>the diagnosis.
>
>Gently done, with thin and flexible plastic catheter such as Pipelle or
>similar (as opposed to the Novak metal curette) without the use of
>tenaculum, and with appropriate premedication with NSAIDs, is often of
>minimal discomfort.
>
>--
>Rafael Haciski, MD FACOG
>Gynecology and Infertility Associates
>Baltimore, MD
>410-825-0020
>web......http://www.IVF-MD.com
>e-mail..GIA@IVF-MD.com
>
>> From: traalblaze@aol.com (guy venezia)
>> Reply-To: ob-gyn-l@obgyn.net
>> Date: Tue, 4 Apr 2000 19:38:03 -0500
>> To: Multiple recipients of list OB-GYN-L <ob-gyn-l@forum.obgyn.net>
>> Subject: Re: luteal phase defects
>>
>> At Tue, 4 Apr 2000, asha wrote:
>>> you can get a good menstrual history and do a mid luteal
>> emb.(full thickness endometrial biopsy) the path will then read it and
>> give you a day in the pts cycle. the endometrium is considered out of
>> phase when the histo dating lags behind the menstrual dating by 3 or
>> more days.
>> technically this should be done in two diff cycles for the diagnsis, but
>> pts are not too happy to do this test twice.
>> i would do it once.
>> you can also check mid luteal progest levels (controversial). progest
>> levels < 10 ng/ml is abnormal.
>> hope this is helpful
>> guy
>>
>>> how do you diagnose luteal phase defects
>>
>> --
>> guy
>>

--
guy




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