Re: GYN: HPV Testing

From: Efrain Ramirez (eramirez@icepr.com)
Fri Mar 24 19:59:05 2000


At Fri, 24 Mar 2000, Garry Siegel wrote: >
>I have begun to selective test for HPV type in paps or tissue in order
>to try and triage follow up better. I am wondering if others have
>started doing so, and if so, what are common scenarios for which they
>test?

I do not do HPV typing -- did for a while years ago (try it)-- not helpful.

>Two cases to discuss:
>
>1. 30 YO who had a cryo years ago, no records, with paps over that last
>3 years intermittently ASCUS or reactive. In 1996, I had seen a couple
>of areas of unimpresssive white epithelium that were squamous atypia on
>biopsy. In 1997, her colpo was normal.
>
>When she was in for a pap recently, she was tested for HPV and was
>postive for a high risk type. The lab screwed up and didn't actually do
>the pap, however. So, I am wondering what follow up she needs short of
>doing a pap, of course. Assuming that her paps don't worsen. . .
>
>Paps 2 or 3 times a year, unless worsened than ASCUS/reactive?
>
>Colpo once or more annually, interspersed with paps?
>
>Other?

Pap and colpo q.-4/12- 6/12

>Tentatively, once I talk to her, I'm likely to have her come in within 4
>to 6 months to do the pap that didn't get run by the lab.
>
>2. 44 nulliparous YO menopausal woman, menopausal after
>surgery/chemo/bone marrow transplant for Breast Cancer, who had a laser
>of her cervix for dysplasia in the late 80s, specifics unknown. After
>her bone marrow a couple of years ago, she came in this year and had CIS
>on her pap, CIS on her biopsy, and a LEEP with CIS/clear margins. Her
>cervix was almost flush with the vagina on one side prior to the LEEP,
>and now looks "worse." Her LEEP tissue was positive for high risk HPV.
>
>Normally, she would have frequent paps over the next year or two, and
>probably every six months forever.
>
>Other options:
>
>Colpos intermittently, realizing that her menopausal vagina and flush
>cervix make colposcopy painful for her, and hard for me.
>
>Hysterectomy
>

Same as before-- Premarin cream prior pap and colpo >
>Garry
>
>--
>Garry E. Siegel, M.D., F.A.C.O.G.
>Roswell, GA
>Private Practice
>

--
"The things you learn after you know everything are the important ones"




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