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Breast CA & HRT/ERTFrom: Joanne Bulley, MD (jbulley@cheshire.net)Wed Feb 16 20:57:03 2000
Hey, Folks - As I recall someone(s) somewhere(s) is/are doing a study on HRT for survivors of Breast Ca that is prospective AND randomized. Who is doing this study and how long before it reaches maturity and analysis and publishing. If I am not hallucinating, the peeks at the data to see if "no Harm" is being done has all been favorable. Somehow, I am more or less of an educated opinion that estrogen is not a carcinogen to the breast, but if a CA developes, it may grow faster because of the hormones as breast is a hormonally responsive tissue. If various HRT were significantly detrimental - it seems we should have already seen increasing death rates etc but the death rate of breast cancer is declining - despite our throwing various HRT regimes at women over the past 30+ years. Early in training the tumor boards were recommending oophorectomies on premenopausal Br Ca patients, then decided it didn't make a difference. I realize that discussing and doing Oophorectomies is coming back in vogue, but does it incontrovertably make a difference? Like Paul, however, I hope to see critical analyses of this stuff by those who are better at I at dissecting out the data! Joanne B
At Wed, 16 Feb 2000, Paul Prior MD wrote:
>The sooner the better. There seems to be a sudden flurry of data that
-- Joanne Bulley, MD Keene, NH
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