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Re: GBS and HRT--Breast caFrom: J. Hellriegel (jhellrie@pce.net)Sat Jan 29 21:33:27 2000
At Sat, 29 Jan 2000, Harnath Holmes wrote: > >Right now I can't even get PCN. The hospital has 3 vials left and their >supplier won't ship any until the fall. Initially I liked the "risk factor >based" way of antibiotic prophylaxsis. Fewr women were treated but the >scenarios of a past GBS + culture or unk GBS culture were eliminated. I >have had babies die of GBS so I know its real. However most of the MFM >groups went right to screening cultures and abandoned the risk factor >approach, therefore I changed to the screening. I have been seeing a lot >more patients turn up positive and therefore am treating a lot more women in >labor. But I am not sure we can take a 'step back' to risk factor triage. > >On the HRT note, Most of their discussion seemed to defend possible bias. >Many of their confidence intervals contained 1.0 which I thought ment they >weren't very confident. In all those women studied they could only find 33 >for one conclusion? Hard to base changing everyone's HRT on 33 women. > -- Agree with above. Does raise questions. Also note that the 11 women on progesterone alone had a relative rate of 0.8.
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