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Re: Bendectin, it's ba-a-a-a-ck! From: Mary Knauer, CNM (mknauer@midwives.org) Sat Jan 8 12:05:43 2000 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: croure@ibm.net: "Re: Episiotomy and Anal Incontinence" Previous message: garrys@mindspring.com: "Re: Episiotomy and Anal Incontinence" In reply to: Dr Eberhard W Lisse: "Re: Referral in NYC" At Mon, 03 Jan 2000, james connerth wrote: > >NOT back in US---you can bank on that!!! > Check out "Pocket Companion to Obstetrics: Normal & Problem Pregnancy" (Gabbe, Neibyl, Simpson, 1999). The Unisom 25 mg and B-6 25 mg combo is suggested as an effective treatment for nausea & vomiting in pregnancy (p 28). Because of the bogus birth defect claims, this drug has probably been studied more closely than most other Cat A & B medications. I'm more confident about its safety than phenergan suppositories. Neibyl reports that while there are no known teratogenic effects of other antiemetics, much less information is availble. Other researchers claim that millions of dollars could be saved in hospital costs if it were brought back on to the market. A patient in my practice is using Bendectin (ordered through a compound pharmacy) for the first time in her third pregnancy. The first two pregnancies had her hospitalized multiple times. She's 24 weeks now and is actually gaining weight--has not required IV hydration at all. >Joanne Bulley wrote: > >> > ------------------------------ >> When I was doing Ob I frequently discussed and offerred the 1/2 Unisom and >> > ------------------------------ >> 10-25 of B6 3-4 X daily as Bendectin sustitute. With the rest of the >> > ------------------------------ >> discussion. It is nice to see SOME logic surfacing on this type of subject. >> The women who had had one pregnancy using it as Bedectin and were in the next >> without it, were DELIGHTED to have the option back. >> >> Joanne Bulley >> > >> > Date: Thu, 30 Dec 1999 17:20:16 -0600 (CST) >> > From: ainsron@msn.com (Ronald E. Ainsworth) >> > >> > I was pleased to read in my December update to Briggs, Freeman & Yaffe, >> > Drugs in Pregnancy and Lactation, that in the August 1999 Federal >> > Register, the FDA added the combination of pyridoxine HCL (10 mg) and >> > doxylamine succinate (10 mg) to tis published list of "approved drug >> > products with therapeutic equivalence evaluations." It is now considered >> > safe and effective and pharmaceutical manufacturers can now file an >> > abbreviated new drug application and market it in the US. Briggs rates >> > it as a category "A" drug in pregnancy. It is hard to believe that drug >> > was taken off the market 21 years ago, just because of "shark attacks," >> > not because of science. In spite of the removal of Bendectin continued >> > to use the OTC combination of Unisom and B6 for my patients with >> > hyperemesis, because it worked so well and the risks were discounted >> > many years ago. It sure made a difference for my own wife! How about >> > the rest of the members of the list? Next message: croure@ibm.net: "Re: Episiotomy and Anal Incontinence" Previous message: garrys@mindspring.com: "Re: Episiotomy and Anal Incontinence" In reply to: Dr Eberhard W Lisse: "Re: Referral in NYC"

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