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Re: Blood TestsFrom: Kelly (anonymous@obgyn.net)Thu, 22 May 1997 09:59:37 -0500 (CDT)
At Wed, 21 May 1997, Sonja wrote: > >Dear Doctors, > >Whilst being worked up for glucose intolerance, my dr has ordered the >following: > >ANF - what is this? Anitnuclear Factor (we call it ANA or antinuclear antibody here in the States). It is used as a test for autoimmune diseases like lupus.
>Anticardiolipin Ab - and this? another autoimmune marker.. Cardiolipin is involved in the blood clotting mechanism.
>APTT - and this?
activated partial thromboplastin time, another measure of blood clotting
and a marker for the lupus anticoagulant
> Positive tests here may indicate an immunologic cause for repeated miscarriage and stillbirth. Small blood vessels in the uterus and placenta clot, decreasing blood flow to the pregancy. This can lead to improper implantation, early miscarriage and stillbirth due to insufficient nutrient and oxygen supply. Immunology is very comple, and my explanations are overly simplistic (and probably not 100% on target), but this is the general idea.
Perhaps Dr. Lovely, our resident reproductive endocrinologist, can
better explain things...hint,hint :-)
>
-- Kelly Shanahan, MD, FACOG S. Lake Tahoe, CA
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