WOMENS-HEALTH Messages for May, 1997: Re: Blood Tests

Re: Blood Tests

From: Kelly (anonymous@obgyn.net)
Thu, 22 May 1997 09:59:37 -0500 (CDT)

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At Wed, 21 May 1997, Sonja wrote: >
>Dear Doctors,
>
>Whilst being worked up for glucose intolerance, my dr has ordered the
>following:
>
>ANF - what is this?

Anitnuclear Factor (we call it ANA or antinuclear antibody here in the States). It is used as a test for autoimmune diseases like lupus.

>Anticardiolipin Ab - and this?

another autoimmune marker.. Cardiolipin is involved in the blood clotting mechanism.

>APTT - and this?

activated partial thromboplastin time, another measure of blood clotting and a marker for the lupus anticoagulant >
>Would you please explain these tests and their significance in relation
>to still birth and glucose intolerance?

Positive tests here may indicate an immunologic cause for repeated miscarriage and stillbirth. Small blood vessels in the uterus and placenta clot, decreasing blood flow to the pregancy. This can lead to improper implantation, early miscarriage and stillbirth due to insufficient nutrient and oxygen supply.

Immunology is very comple, and my explanations are overly simplistic (and probably not 100% on target), but this is the general idea.

Perhaps Dr. Lovely, our resident reproductive endocrinologist, can better explain things...hint,hint :-) >

-- Kelly Shanahan, MD, FACOG S. Lake Tahoe, CA

note: Opinions here are for educational purposes only. This information is not intended to supplant the need for you to consult with your own physician. It cannot take the place of a face to face consultation and examination.

Next message: Susan: "Terminology hysterectomy pathology report"
Previous message: Kelly: "Re: alt.tx. post hysterectomy"
In reply to: Sonja: "Blood Tests"
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Reply: Laurie: "Re: Blood Tests"

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