WOMENS-HEALTH Messages for May, 1997: Re: antiphospholipid antibodies

Re: antiphospholipid antibodies

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Mon, 19 May 1997 23:03:10 -0500 (CDT)

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At Mon, 19 May 1997, Kelly wrote: >
>At Sun, 18 May 1997, MO wrote:
>>
>>Hi
>>
>>We are looking for information on immunological barriers to pregnancy,
>>specifically the APA test, which some doctors only recognize if it
>>includes at least 18 specific sub tests.
>>
> can anyone tell us what
>>the names are of the individual items so we can ask the lab?
>
>The components are(at least in the lab we use):
> Lupus anticoagulant
> cardiolipin IgG, IgM and IgA antibodies
> phosphatidyl serine IgG, IgM and IgA antibodies
> phosphatidic acid IgG, IgM and IgA antibodies
> phosphatidyl ethanolamine IgG, IgM and IgA antibodies
> phosphatidyl choline IgG, IgM and IgA antibodies
>
>That's only 16, but it is what is included in the "expanded APL
>syndrome" evaluation here.

Dr. Shanahan, as always ;-) , is quite right. Many articles, of late, have discussed the "fact" that the only important antibodies in this category are Anti-cardiolipin antibody (ACA) associated with repeated miscarriages, future blood clotw and other problems.......and lupus anticoagulant (LAC). Many investigators feel that the other antibodies are of little to no importance. Or, as my son would say "Slim to none, and slim just left town!"

-- Harvey S. Marchbein, M.D. FACOG, FACS OBGYN.net U.S. Representative, New York Great Neck, New York http://www.obgyn.net/states/bios/marchbein.htm http://www.obgyn.net/women/heroes/harveym.htm

*Note: Opinions expressed here are for educational purpose only. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options.

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