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Re: Question on Single Umbilical Artery PregnanciesFrom: Joel (anonymous@obgyn.net)Tue, 06 May 1997 13:30:03 +0200
Geffrey H. Klein, MD wrote: > > Hello all. Sorry to > >submit a question to > >you all but I'm struggling to find a place > >to ask this question. > > > >My sister-in-law is 38 years old. She is > >starting her 5 month of pregnancy and has > >just been informed (through an amnio) that > >she has a single umbilical artery that is now > >feeding her unborn child. In addition she > >was told that they found 2 markers and > >chromosome 13 and 21. Excuse my terminology. > >I have no medical background whatsoever. > > > >Anyway, she's struggling on trying to decide > >if she should have this baby. Her OBGYN has > >not gotten into any details with her and describe > >to her any seriousness this could be. > > > >What are the potential birth defects or > >proven baby's that have been born with only > >being fed through a single umbilical artery. > >And have some babies survived this without > >any problems? > > > >If you could respond asap that would be great!! > >She only has until the beginning of next > >week to decide if she should continue on > >with her pregnancy. > > I direct you to this study: > > Authors > Blache G. Garba A. Frairot P. Vancina S. Gaja R. > Institution > Service de Gynecologie-Obstetrique, Centre Hospitalier General, Roanne. > Title > [Prognostic value of a single umbilical > artery. 87 cases]. [Review] [34 refs] [French] > Source > Journal de Gynecologie, Obstetrique et Biologie de la Reproduction. > 24(5):522-8, 1995. > Abstract > OBJECTIVE. To study the effect of a single > umbilical artery on infant prognosis. > METHOD. Unicentric retrospective case-control study based on 18,425 births > and semi-late pregnancy interruptions. RESULTS. There were > 87 cases of single umbilical > artery, frequently associated with a familial history of > malformation in the sibhood (6.8%), gravid pathology (hypertension 11.5%, > diabetes 6.8%), funicular anomaly (32%). One or several malformations were > seen in 21% of the infants, the main cause of infant mortality (9%) and > morbidity. The case-control study demonstrated that single > umbilical artery corresponded to a moderate > reduction in weight (-310 g), term (-1.4 weeks gestation), AGPAR scor at 1 > and 5 minutes (-0.7) which was not significant when single > umbilical artery was the sole pathology. > CONCLUSION. When occurring alone, single > umbilical artery has little effect on > infant prognosis which is more dependant on associated malformations and > gravid pathologies determining antenatal and postnatal management. > [References: 34] > > What it says is that found alone without other anomalies, a single > umbilical artery is of no serious consequence > > Best of luck... I've made a study on Single Umbilical artery. I agree with that conclusion : if alone, no problem. BUT you must have a very performant US exam, not a routin one. I can send you the whole text of the study Geffrey spoke of, but it's in French ! Let me know your personnal post adress if you want it.
-- Joel Kompanietz, M.D. CNGOF, OBGYN.net International Representative, France Mazamet, France
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