WOMENS-HEALTH Messages for May, 1997: Re: Question on Single Umbilical Artery Pregnancies

Re: Question on Single Umbilical Artery Pregnancies

From: Geffrey H. Klein, MD (anonymous@obgyn.net)
Mon, 5 May 1997 23:54:12 -0600

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Hello all. Sorry to >submit a question to
>you all but I'm struggling to find a place
>to ask this question.
>
>My sister-in-law is 38 years old. She is
>starting her 5 month of pregnancy and has
>just been informed (through an amnio) that
>she has a single umbilical artery that is now
>feeding her unborn child. In addition she
>was told that they found 2 markers and
>chromosome 13 and 21. Excuse my terminology.
>I have no medical background whatsoever.
>
>Anyway, she's struggling on trying to decide
>if she should have this baby. Her OBGYN has
>not gotten into any details with her and describe
>to her any seriousness this could be.
>
>What are the potential birth defects or
>proven baby's that have been born with only
>being fed through a single umbilical artery.
>And have some babies survived this without
>any problems?
>
>If you could respond asap that would be great!!
>She only has until the beginning of next
>week to decide if she should continue on
>with her pregnancy.

I direct you to this study:

Authors Blache G. Garba A. Frairot P. Vancina S. Gaja R. Institution Service de Gynecologie-Obstetrique, Centre Hospitalier General, Roanne. Title [Prognostic value of a single umbilical artery. 87 cases]. [Review] [34 refs] [French] Source Journal de Gynecologie, Obstetrique et Biologie de la Reproduction. 24(5):522-8, 1995. Abstract OBJECTIVE. To study the effect of a single umbilical artery on infant prognosis. METHOD. Unicentric retrospective case-control study based on 18,425 births and semi-late pregnancy interruptions. RESULTS. There were 87 cases of single umbilical artery, frequently associated with a familial history of malformation in the sibhood (6.8%), gravid pathology (hypertension 11.5%, diabetes 6.8%), funicular anomaly (32%). One or several malformations were seen in 21% of the infants, the main cause of infant mortality (9%) and morbidity. The case-control study demonstrated that single umbilical artery corresponded to a moderate reduction in weight (-310 g), term (-1.4 weeks gestation), AGPAR scor at 1 and 5 minutes (-0.7) which was not significant when single umbilical artery was the sole pathology. CONCLUSION. When occurring alone, single umbilical artery has little effect on infant prognosis which is more dependant on associated malformations and gravid pathologies determining antenatal and postnatal management. [References: 34]

What it says is that found alone without other anomalies, a single umbilical artery is of no serious consequence

Best of luck...

-- Geffrey H. Klein, MD listowner: OB-GYN-L Advisory Board Chairman, OBGYN.net < http://www.obgyn.net > Co-moderator: sci.med.obgyn gklein@bcm.tmc.edu gklein@icsi.net

*Note: Opinions expressed here are for educational purpose only. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options.

Next message: Joel: "Re: Question on Single Umbilical Artery Pregnancies"
Previous message: Kelly: "Re: TUBAL SSURGERY"
In reply to: Roberta: "Question on Single Umbilical Artery Pregnancies"
Next in thread: Joel: "Re: Question on Single Umbilical Artery Pregnancies"

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