WOMENS-HEALTH Messages for July, 2008: Re: ONCOLOGY: VIN 2 Differentiated

Re: ONCOLOGY: VIN 2 Differentiated - Biopsy Pathology Report

From: Mom (anonymous@obgyn.net)
Sun, 27 Jul 2008 10:16:33 -0500 (CDT)

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PART II----------------

MY QUESTIONS: PART II---------------- 1. Is it likely that the precancerous nodule found in her colon and PART II---------------- this are related...and should we be seeing an Oncologist to put this all together (I called our GP and they said no, they're probably unrelated)? 2. From the report, she has the Differentiated type which everyone says is not caused by HPV, although she obviously has HPV from the Pathology report. Is there a reason to test for which type of HPV she has? Are these (her HPV and VIN) really unrelated? 3. Are there other tests she should have to look for cancer/cysts in other areas- PAP (not due for one until fall), mammogram (she now tells me she's had a few small bumps between her breast/armpit for about 5 years. I/Mom have many breast cysts-they say benign.), other scans? 4. After hearing about the cysts, I was expecting it to be the HPV genital warts, but I immediately asked our GYN if the Pathology showed genital warts, but she confirmed she spoke to the Pathologist and it was a epidermal cysts and not the warts. The Pathology report says the cyst is benign. Does this mean the cysts are really unrelated and the VIN is just in the surface skin above it? If so, it sounds like she was lucky they found this at all?! 5. I don't know what the treatment will be, but it doesn't sound like laser is the way to go. I'm reading since she has the bumps in haired areas that excision may be better? Isn't it always better to be able to get the pathology, which is destroyed with laser/freezing? 6. It sounds like there's a large correlation with finding this differentiated VIN adjacent to areas with Vulvar Cancer. Is just removing the other cysts going to be enough? If she really doesn't have any skin changes and just the cysts below, how can they find it all? 7. Since they also call this Differentiated type "Simplex". Does this mean it has anything to do with Herpes Simplex? The only thing I've read is a correlation with the Usual VIN and having Herpes Simplex in some, but no mention with Differentiated. 8. The VIN Differentiated sounds like it's VERY unusual (reading 2-10% of all VIN) and EXTREMELY unusual in someone her age (sounds like the mean age is in the 60's for this type, 50's for usual VIN-but found sometimes in women in their 20's). In fact I haven't found mention yet of anyone her age diagnosed with it. Hopefully they won't find any Cancer at this point, but given her age and the precancer in her colon, we're really concerned about her long-term care, screening and prognosis. Is there any great source for us? 9. What else should we be doing/know? Sorry for the length, but I didn't want to be incomplete. Thanks for your help!

--
Concerned Mom (and Dad)

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