WOMENS-HEALTH Messages for July, 2008: Re: CONCURRENTHPV&HSV: Concurrent hrHPV & HSV-2 inevitable cervical cancer?

Re: CONCURRENTHPV&HSV: Concurrent hrHPV & HSV-2 inevitable cervical cancer?

From: Ellen (anonymous@obgyn.net)
Sat, 19 Jul 2008 11:28:23 -0500 (CDT)

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At Sat, 19 Jul 2008, Ellen wrote: >
>Dear Doctors:
>
>I have had HSV-2 for 4 years since 2004 (only found out recently as
>symptoms suddenly surfaced) and 2 years ago was infected with hrHPV. The
>hrHPV has persisted for 2 years according to the Digene HC II. Is
>cervical or other genital cancers in my future inevitable? I recognize
>that HPV clearance occurs within 12-24 months and I have passed that
>timeframe. Are there statistics I could look to to determine what my
>risk is given that I have HSV and hrHPV coinfection? I know it's the
>highest it can possibly be because HSV and hrHPV together further
>increase risk of cervical and other genital cancers. I have HSV-2 of
>the genital tract.
>
>What other precautions, other than the common sense lifestyle ones,
>could I make? I don't smoke, have a great diet and relatively fit, but
>may have some autoimmune issues going on. I don't know why else my HPV
>would persist so long.
>
>Thanks for any advice. Ellen

Sorry Doctors, I neglected to mention that my first pap was biopsy proven CIN1 prompted by LSIL with HPV effects and hrHPV+ for one or more strains. Two subsequent paps showed "negative for intraepithelial lesion or malignancy" but still hrHPV+ every time. I have tested hrHPV+ consistently over the course of two years and during the time I was infected with hrHPV, my formerly-dormant HSV-2 spiraled out of control. Previously my HSV was so completely dormant, I had utterly NO idea I had herpes.

1) Is "negative for intraepithelial/malignancy..." the new terminology for WNL? 2) Does HPV cause HSV to worsen and vice versa?

Thanks.

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