WOMENS-HEALTH Messages for April, 2008: Re: THYROID: Elevated Androgens & Thyroid antibodies

Re: THYROID: Elevated Androgens & Thyroid antibodies

From: Walter Futterweit, MD, FACE,FACP (anonymous@obgyn.net)
Mon, 28 Apr 2008 17:56:08 -0500 (CDT)

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Reply: Kate: "Re: THYROID: Elevated Androgens & Thyroid antibodies"

At Sun, 27 Apr 2008, Kate wrote: >
>I understand that there is an increased prevalence of thyroid
>auto-immunity amongst PCOS patients. In your findings, is this correct?
>
>In June of 07 my labs came back showing elevations in:
>Testosterone, serum: 79 ng/dl (14-76)
>Testosterone, Free: 1.12 ng/dl (.10-.85)
>dhea-s: 324 ug/dl (45-270)
>
>as well as elevated Cholesterols (but in range triglicerides)
>
>As well, I have shown elevations in:
>Throglublin Antibodies: 47, down to 43 and recently, down to 41 (upper
>reference being 40)
>and elevated TSI (thyroid stimulating immunoglobulins):134 (upper
>reference being 130)
>TSH within range but felt horribly when at it's highest (on paper,
>anyway) which was 3.70
>
>My doctor seems to think these are just my "normal" but I have a hard
>time accepting this, in light of symptoms (which I expressed, long
>before these labs were drawn) as being normal. As well, I have gained
>considerable weight, which outside of pregnancy, is unlike me.
>
>Is there anything my doctor should consider, that may help them make a
>diagnosis? Life's too short to feel this badly.
>
>The only medication I am taking is Lexapro. For a-while, I was taking
>BC Pills to regulate my menses but they didn't work for me. My doctor
>wanted to see what my own system would do, being off of them.
>
>Since the birth of my last child, 3 years ago, my hormones have never
>really gotten back on track.
>
>Thank you for your time,
>
>A 36 year old woman

Dr.Futterweit: PCOS does NOT have an increased incidence of thyroid autoantibodies in the majority of papers written on this. I also studied this in 1988, and found that PCOS women and normal women have the same prevalence. By the way, in a young woman, any woman, a TSH near 4.0 appears to be an indicatetion for readjusting you thyroid status with positive thyroid autoantibodies for subclinical hypothyroidism with a small dose of synthroid, about a 50 ug tab daily. Best wishes, Dr.Futterweit

--
Walter Futterweit, MD, FACP, FACE
Clinical Professor of Medicine, Division of Endocrinology
Mount Sinai School of Medicine, New York, NY 10029
http://www.aacehost.com/pages/page.php?r=716

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