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Re: transdermal Progesterone

From: BJ (anonymous@obgyn.net)
Tue, 28 May 2002 19:43:19 -0500 (CDT)


At Tue, 28 May 2002, D.N. wrote: >
>Hi,
>
>I know that transdermal progesterone cream is not considered to be a
>reliable route of delivery.
>
>I wonder, if they are able to make an estrogen patch for HRT, what about
>a progesterone patch? Do you know if anything like that is in
>development?
>
>Why is it that estrogen can be delivered thru the skin reliably, but
>progesterone cannot?
>
>Thanks for your time.
>
>--
>D.N.
>

You are mistaken in believing that transdermal progesterone is not absorbed. There are several studies using saliva testing that prove it is, in fact, absorbed very quickly compared to oral administration. The real issue is whether or not blood level testing is accurate and it is not because it does not measure bioavailable hormone. Your question about estrogen patches is exactly the correct logic.




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