Re: HPV?-Reply to Dr. Marchbein...!
From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sun, 26 Aug 2001 20:52:59 -0500 (CDT)
At Sun, 26 Aug 2001, Melanie wrote:
>
>Thanks VERY much for your response.
>
>The colposcopy/biopsy was supposedly done to confirm the HPV diagnosed
>(or misdiagnosed) at the first Pap screening (an HPV DNA panel was done
>at that time....low-risk was supposedly the outcome....)
Then that's the answer about the HPV. It can either be done as a
separate test or if a thin prep pap is done, it can be done on the same
specimen as a "reflex" HPV. The test you had is definitive, not
speculation and not open to theoretical debate.
>
>QUESTIONS:
>
>1) Does the biopsy diagnosis of <<Parakeratotic squamous mucosa with
>parabasal cell hyperplasia>> confirm HPV?
Nope.
>My gut sense is it does
>NOT....And that's why you're suggesting the HPV cervical sample....(AND,
>if this test you're suggesting is different from the HPV DNA panel
>that's already been done, it stands to reason it should have been done
>on the tissue samples from the biopsy, if the Dr. ORDERED the biopsy to
>confirm HPV!!! I shouldn't have to go back for it, if you know what I
>mean!)
In this post I now know that you had the separate HPV test so further
testing with respect to that is unnecessary.
>2) PLEASE translate <<Parakeratotic squamous mucosa with parabasal cell
>hyperplasia>> into simple layman's language. I need to know what it
>means.
Not a problem is what it means - a variation of normal - not a disease.
Hope this helps and write back anytime for more information.
HSM
>(PS...I live on Long Island as well. My breast surgeon is in Lake
>Success, Karen Kostroff....)
>
>Again, thank you very much for your response....
>
>At Sun, 26 Aug 2001, Harvey S. Marchbein, M.D. wrote:
>>
>>Simple answer. Get an HPV low risk/ high risk cervical sample to get
>>the answer rather than debate the possibilities. Once that is back, the
>>discussion can begin.
>>
>>Hope this helps and write back anytime for more information.
>>
>>HSM
>>
>>At Sun, 26 Aug 2001, Melanie wrote:
>>>
>>>At Wed, 22 Aug 2001, Melanie wrote:
>>>>
>>>>At my yearly pap screening brief, I was told that HPV was
>>>>found on the cervix. I then went for a colposcopy/w biopsy; two
>>>>"abnormal" spots were sampled, but no veneral warts were seen. The path
>>>>report for the biopsy doesn't specifically mention HPV, but states a diagnosis
>>>>of <<Parakeratotic squamous mucosa with Parabasal cell Hyperplasia>>
>>>>
--
Harvey S. Marchbein, M.D. FACOG, FACS
Great Neck, New York
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