WOMENS-HEALTH Messages for February, 2000: Re: POF?

Re: POF?

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Mon, 28 Feb 2000 18:56:39 -0600 (CST)

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In reply to: martha: "POF?"

At Sun, 27 Feb 2000, martha wrote: >
>Dear Doctor,
>Im 21 years old, had an early menstruation at 8 and had been diagnosed
>with hypothyroidism since that time.
>I stopped taking thyroxine for ten years even with hypothyroidism and
>had regular menstruation. I resumed taking thyroxine again in 1997, I
>think. However,in 1998, I experienced spotting and noticed that I had
>lighter menstruation. I consulted the gynecologist and I had undergone
>tsh, free t4, cbc and pelvic ultrasound. The gyn mentioned nothing
>wrong and prescribed no medicine. She thought that it was just due to
>my being overweight. I weigh 145 lbs. and my height is 5'. My periods
>gradually went back to normal.
>I used to menstruate for seven days used three pads in a day but I think
>around 1996-1997 it reduced to four days and I used two pads in a day.
>However,last December,I experienced spotting again. I went back to the
>gyn.This time she prescribed primolut n. Last January, there's spotting
>on the first day, and became heavier in the next few days. But, the gyn
>considered it light since I change pads once only in a day, which means
>I can use one pad the whole day. She prescribed prempak, then , this
>month ,spotting again on the first two days, became heavier only on the
>fifth day. My period lasted for eight days though I consider it light.
>I was instructed to take prempak for two more cycles.
>In 1998, when I had spotting,I don't think I'm under stress.
>But,this past months, I'm under stress.
>In 1996, before I resumed the thyroxine intake and experienced
>spotting,I had very profuse watery discharge for two months. My gyn
>said I was fertile at these time. I don't usually experience this.My
>endocrinologist advised me to stop taking thyroxine since my goiter is
>smaller.
>
>My questions are- will prolonged untreated hypothyroidism cause
>premature ovarian failure?

No. However, some hypothyroidism is from auto-immune antibodies to the thyroid AND when this happens, there can be other auto-immune endocrine problems, one of which is anti-ovarian antibodies which have been associated with POF. Whew! This needs to be checked by your endocrinologist.

>Do you think I'm headed for it.

No way of telling but I am curious about the possibility of PCO. Were your FSH and LH normal and was a pelvic sonogram done? With excess weight and menstrual irregularities, PCO should be ruled out. If it is PCO, glucophage (written about many times in the archives) might be the treatment of choice.

>What is
>primary hormonal problem? Is it the same with POF?

Answered circuitously above.

>Sincerely yours,
>Martha

--
Harvey S. Marchbein, M.D. FACOG, FACS
Great Neck, New York

**Note:  Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.

**Private emails cannot be entertained due to time constraints,
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**Thank you for your understanding ;-)

Next message: Harvey S. Marchbein, M.D.: "Re: clotting during period"
Previous message: C Twisdale RN: "Re: very early stages of pregnance"
In reply to: martha: "POF?"

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