mid-term femur length trisomy risk query

From: Mary Willmann (fizztastic@talk21.com)
Tue Nov 15 12:33:09 2005


The patient is 40 years old; her partner is 50. This is their first pregnancy. They are very concerned about age-related risk of chromosomal abnormalities, but opted against CVS and then amnio when 1st trimester screening adjusted their background trisomy 21 risk to 1:272 and trisomy 13/18 risk to 1:843.

The mother is above average height (183 cm) and the father is below average height (168 cm). Both are Causasian. My question is this: at 21 weeks + 3 (dated by known LMP), the femur length of the fetus is 33.5 mm. (Other measurements taken at the same time include BPD 53 mm; HC 182 mm; TCD 21 mm; CM 5 mm and AC 161 mm.) Is this low enough to warrant concern? Urgently seeking advice. Any comments would be gratefully received. Thanks very much.

Mary




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