Re: Does hypochorionic hemorrhage alters triplo-test results?'reply'
From: Latha Natarajan (nattu@bgl.vsnl.net.in)
Thu Apr 1 21:16:49 2004
Maternal Serum AFP levels go up with haemorrhage.
LN.
>----- Original Message -----
From: "art fougner, md" <evsono@pipeline.com>
To: "Multiple recipients of list ULTRASOUND" <ultrasound@dns.obgyn.net>
Sent: Friday, April 02, 2004 12:19 AM
Subject: Re: Does hypochorionic hemorrhage alters triplo-test
results?'reply'
> But how were the maternal serum screens specifically affected by
> "threatened miscarriage"?
>
> art
>
> At Wed, 31 Mar 2004, AFPPLUS3@aol.com wrote:
> >
> >This may help you with regards to adjusting the patients risk...
> >
> >Threatened abortion: A risk factor for poor pregnancy outcome, a
> >population-based screening study
> >Joshua L. Weiss, MD,* Fergal D. Malone, MD, John Vidaver, MA, Robert H.
Bal ,
> >MD,
> >David A. Nyberg, MD, Christine H. Comstock, MD, Gary D. Hankins, MD,
Richar
> >L. Berkowitz, MD, Susan J. Gross, MD, Lorraine Dugoff, MD, Ilan E.
> >Timor-Tritsch, MD, Mary E. Dâ?TAlton, MD, for the FASTER Consortium
> >Columbia Presbyterian Medical Center, New York, NY
> >â?"
> >Objective: The purpose of this study was to determine whether patients
with
> >first-trimester threatened abortion are at increased risk for poor
pregnanc
> >outcome.
> >Study design: A large prospective multicenter database was studied.
Subject
> >were divided into three groups: (1) no bleeding, (2) light bleeding, and
(3
> >heavy bleeding. Univariate and multivariable logistic regression analyses
w re
> >used.
> >Results: The study comprised 16,506 patients: 14,160 patients without
> >bleeding, 2094 patients with light bleeding, and 252 patients with heavy
bl eding.
> >Patients with vaginal bleeding, light or heavy, were more likely to
experie ce a
> >spontaneous loss before 24 weeks of gestation (odds ratio, 2.5 and 4.2,
> >respectively) and cesarean delivery (odds ratio, 1.1 and 1.4,
respectively) Light
> >bleeding subjects were more likely to have preeclampsia (odds ratio,
1.5),
> >preterm delivery (odds ratio, 1.3), and placental abruption (odds ratio,
1. ).
> >Heavy vaginal bleeding subjects were more likely to have intrauterine
growt
> >restriction (odds ratio, 2.6), preterm delivery (odds ratio, 3.0),
preterm
> >premature rupture of membranes (odds ratio, 3.2), and placental abruption
( dds
> >ratio, 3.6).
> >Conclusion: First-trimester vaginal bleeding is an independent risk
factor
> >for adverse obstetric outcome that is directly proportional to the amount
o
> >bleeding.
> > 2004 Elsevier Inc. All rights reserved.
> >KEY WORDS
> >Threatened abortion
> >Spontaneous pregnancy
> >loss
> >Preterm delivery
> >Placental abruption
> >Preterm premature
> >rupture of membranes
> >â?"
> >First-trimester vaginal bleeding is a common complication that affects
16% o
> >25% of all pregnancies.1,2 When pregnant patients have bleeding, it may
cau e
> >stress and anxiety for the mother-to-be about the future outcome of the
> >pregnancy. In general, the incidence of
> >spontaneous abortion after first-trimester bleeding is quoted to be 50%
> >before sonographic evaluation for fetal viability.1,3 If a viable fetus
is oted at
> >ultrasound examination after first-trimester vaginal bleeding, 95% to 98%
o
> >such pregnancies will still continue beyond 20
> >weeks of gestation.1,4 Supported by grant No. RO1 HD 38652 from the
National
> >Institutes of Health and the National Institute of Child Health and Human
> >Development.
> >* Reprint requests: Joshua L. Weiss, MD, Columbia Presbyterian
> >Medical Center, 622 W 168th St, PH-16-66, New York, NY 10032.
> >E-mail: jw791@columbia.edu
> >http://www.elsevier.com/locate/ajog
> >
> >American Journal of Obstetrics and Gynecology (2004) 190, 745-50
> >
> >Leonard H. Kellner
> >Lenetix Medical Screening Laboratory, Inc.
> >
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>
> --
> art fougner, md
> ich bin ein New Yorker
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