Re: pregnancy and condyloma

From: Braun, R. Daniel (rbraun@iupui.edu)
Wed Feb 24 08:05:04 1999


Rafael you missed part of the question. It was "Since Progesterone is a Class X drug, then why do many IVF programs use it. Dan

R. Daniel Braun, MD FACOG Clinical Professor Department of Obstetrics and Gynecology Indiana U. School of Medicine Indianapolis, IN

-----Original Message----- From: Rafael Haciski, MD [SMTP:haciski@earthlink.net] Sent: Tuesday, February 23, 1999 11:23 PM To: Multiple recipients of list Subject: Re: pregnancy and condyloma

Roger Klam, M.D. wrote: >
> Then why do many IVF programs use progesterone in the luteal phase
of the > cycle and continue for 12 weeks of pregnancy?

Two main reasons:

1... with such a gargantuan effort as IVF, you do not want any surprises, even minor ones, which may negatively affect the outcome; administering progesterone suplementation is a form of insurance against such impediments;

2... strong follicular stimulation seems to be frequently associated with a sudden, premature, and precipitous

drop in progesterone production by the resultant corpus luteum (or lutea) - replacement with natural progesterone does not add any risk (same progesterone as is secreted by corpus luteum) while preventing the possible adverse effect on the pregnancy by too low progesterone levels;

Supplementation is continued beyond the 8th week at which time (+ or - a week or two) the corpus lutem normally ceases production of progesterone and placenta begins its own progesterone production.

Rafael Haciski, MD FACOG Gynecology & Infertility Assoc. Baltimore MD http://www.ivf-md.com





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