Re: Repeated Hydatidiform Mole

From: Bert Gold (bgold@ktb.net)
Sun Feb 14 18:31:35 1999


Have the mom's chromosomes been run? The most frequent type of complete hydatidiform mole is a 46,XX homozygote formed by the fertilization of an empty ovum by a single haploid sperm that later duplicates its chromosomes to give a diploid tumor. High resolution chromosome mapping (a la Jorge Yunis), especially of X might be informative. There are sibships predisposed to this, though rare. An accurate diagnosis may provide clue to a cure:

On Friday, February 12, 1999, Yu Mao wrote:

> >This patient has already 4 times of hyditidiform mole, but she has not
> >jet a child.
> >

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Bert Gold, Ph.D. Vita brevis Research and Development Ars longa SmithKline Beecham Occasio praeceps Clinical Laboratories, Inc. Experientia fallax 7600 Tyrone Avenue Judicium dificile Van Nuys, California USA 91405 -Hippocrates bgold@ktb.net bert.gold@sb.com VOICE: 818-376-6332 http://www.ktb.net FAX: 818-376-6387

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